Director, Program Management

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC‑6236), a RAS(ON) multi‑selective inhibitor; elironrasib (RMC‑6291), a RAS(ON) G12C‑selective inhibitor; zoldonrasib (RMC‑9805), a RAS(ON) G12D‑selective inhibitor; and RMC‑5127, a RAS(ON) G12V‑selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

This is an exciting, high‑profile, and highly visible Program Management opportunity to advance a first‑in‑class RAS(ON) inhibitor through clinical development. The ideal candidate is a very proficient and self‑motivated program manager with a solid understanding of drug development. The Director, Program Management partners with the Project Team Leader (PTL) on the translation of program strategy into an efficient execution plan; they understand the competitive landscape and clinical context to manage the cross‑functional dependencies and connections.

They understand the breadth of cross‑functional activities and can foster productive collaborations to ensure successful execution.

Key Responsibilities

• Partner with the PTL in defining program strategy, stakeholder management, and overall program leadership topics.
• Establish and maintain functionally integrated project plan and project assumptions (accounting for goals, key objectives, deliverables, risks) to enable accurate project, financial, and portfolio analyses for business planning processes.
• Ensure identification and management of program risks; working with subject‑matter experts to construct appropriate mitigation plans.
• Evaluate alternative development scenarios (comprising costs, timelines, risks, and project strategy) during progression of the program through stage gates and as per business need.
• Lead the global development team through the preparation and update of key project documents and communications.
• Lead an efficient information flow within the global cross‑functional project team, and internal advisory & governance bodies.
• Demonstrate effective meeting and information management including prioritizing the right topics for discussion, ensuring the objectives of the meeting are achieved, communicating decisions to key stakeholders and ensuring that action items are assigned and completed in a timely manner.
• Serve as the owner of project team information including the project plan, budget and program assumptions as approved by PRG and the Senior Leadership Team.
• Partner with the PTL to ensure the team achieves and maintains a high‑level of sustainable performance.
• Apply drug development expertise to coach and mentor project team members to ensure efficient and effective project team operation.
• Identify, recommend, and implement opportunities for streamlining team and business processes.
• Participate in establishment and implementation of project management systems and best practices.
• Coach and mentor members of the Program Management team to ensure a strong bench of future leaders.
• Support new corporate development activities or other initiatives supporting department, portfolio, or corporate needs.

Required Skills, Experience and Education

• B.A. or B.Sc. in Life Sciences and at least 8 years’ experience in the biotech/pharmaceutical industry with at least 5 years’ direct development project management experience managing cross‑functional global development teams.
• Broad knowledge of the clinical drug development process and regulations, coupled with strong proficiency in project management practices, tools, and methodology.
• Expertise in developing and managing project scope, deliverables, risk & resource requirements including schedule, timeline management, and risk management.
• Excellent interpersonal skills, including clear, succinct, and timely communication and proven ability to foster important relationships with key stakeholders.
• Outstanding verbal and written communication skills with the ability to summarize complex information into simple concepts; ability to effectively interact across team functions and with external key stakeholders.
• Proven track record of good decision making and exercising sound judgment.
• Experience using Project Management software to manage project timelines and resources (e.g., MS Project, SmartSheet, OfficeTimeline, and OnePager Pro).
• Strong computer proficiency with MS Office suite, SharePoint, and similar document archiving systems.

Preferred Skills

• M.S.C., M.B.A., or Ph.D. in Life Sciences is a plus.
• PMP (Project Management Professional) or other PM certification or equivalent is a plus.
• Experience in oncology therapeutic area is strongly preferred.

Base Pay Salary Range

The base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA is $211,000 — $264,000 USD.

Revolution Medicines is an equal‑opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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