(Sr) Scientist, RNA Analytical Development

Scientist / Senior Scientist, RNA Analytical Development

You are an analytical development scientist with deep expertise in RNA modalities, someone who thrives at the intersection of method development, platform scalability, and translational impact. You want to build analytical systems that become the backbone of an entire RNA therapeutics engine.This organisation is building a biotech‑like translational engine designed to take novel oligo, mRNA, and conjugate programs from discovery into the clinic. Modern labs, new equipment, and a rapidly scaling team mean your analytical leadership will shape how the entire platform operates.

The RoleAs Scientist / Senior Scientist, RNA Analytical Development, you will build and execute phase‑appropriate analytical strategies for raw materials (novel lipids, pDNA, ligands), drug substances (mRNA, ASOs, siRNA, gRNA), and drug products (LNPs and conjugated oligos). You will define CQAs, develop orthogonal analytical workflows, enable high‑throughput method development, and ensure the platform generates high‑quality material for pipeline programs.

Key ResponsibilitiesDevelop analytical characterization strategies for RNA raw materials, DS and DPImplement orthogonal analytical workflows (HPLC, LC‑MS, CE, UV, qPCR, DLS, TEM)Build scalable, phase‑appropriate workflows to support discovery → IND programsDevelop SOPs, validation plans, and maintain rigorous documentation (LIMS/ELN)

About YouPhD in Analytical Chemistry, Pharmaceutical Sciences, or related disciplineDeep expertise with LC‑MS, HRMS, CE‑SDS, and multiscale purification techniquesHands‑on experience analysing modified oligos and ligand‑oligo conjugates

LogisticsFull‑time, Singapore‑based role within a rapidly scaling translational organisation.If you are motivated by building cutting‑edge RNA analytical platforms from the ground up, we would love to hear from you.